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A Comprehensive Analysis of A-PVP: Chemical Structure, Properties, and Uses

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A-PVP, also known as alpha-pyrrolidinovalerophenone, is a chemical compound with significant implications in both legitimate research and illicit drug trade. In this article, we provide an in-depth examination of the molecular structure, physical properties, chemical reactivity, and pharmacological effects of A-PVP, elucidating its diverse characteristics and applications.

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A-PVP is a synthetic stimulant belonging to the cathinone class of compounds. Its molecular structure and pharmacological effects bear resemblance to other psychoactive substances such as cathinone and methamphetamine. A-PVP has gained popularity as a recreational drug due to its stimulant properties and euphoric effects.

Molecular Structure

The molecular structure of A-PVP comprises a pyrrolidinyl group attached to a valerophenone backbone. This configuration is characteristic of cathinone derivatives and contributes to the compound’s psychoactive properties.

Physical Properties

A-PVP typically appears as a white to off-white crystalline powder or fine crystals. It is highly soluble in organic solvents such as ethanol and acetone but exhibits limited solubility in water. The compound may exhibit polymorphism, leading to variations in its physical appearance and properties.

Chemical Reactivity

A-PVP displays reactivity towards various chemical reagents, enabling its conversion into different derivatives through synthetic routes. Key transformations involved in its synthesis include ketone reduction, alkyl substitution, and functional group modification.

Pharmacological Effects

A-PVP acts primarily as a central nervous system stimulant, exerting effects such as increased alertness, euphoria, and heightened energy levels. However, its use is associated with a range of adverse effects, including hypertension, tachycardia, and psychosis. Long-term or excessive consumption of A-PVP can lead to addiction and serious health consequences.


In summary, A-PVP is a compound with diverse chemical properties and pharmacological effects. Its role as a recreational drug underscores the importance of regulatory measures and public health interventions to mitigate its misuse and associated harms.

Information for preparing this article was taken from the site:

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